1. Aoi W, Hirano N, Lassiter DG, Björnholm M, Chibalin AV, Sakuma K, Tanimura Y, Mizushima K, Takagi T,

   Naito Y, Zierath JR, Krook A.  Secreted protein acidic and rich in cysteine (SPARC) improves glucose

   tolerance via AMP-activated protein kinase activation.  FASEB J 33: 10551-10562, 2019

 

2. Tabata S, Aizawa M, Kinoshita M, Ito Y, Kawamura Y, Takebe M, Pan W, Sakuma K.  The influence of isoflavone

    for denervation-induced muscle atrophy.  Eur J Nutr 58: 291-300, 2019

 

3. Asami Y, Aizawa M, Kinoshita M, Ishikawa J, Sakuma K. Resveratrol attenuates denervation-induced

    muscle atrophy due to the blockade of atrogin-1 and p62 accumulation.  Int J Med Sci 15: 628-637, 2018

 

4. Sakuma KKinoshita M, Ito Y, Aizawa M, Aoi W, Yamaguchi A.  p62/SQSTM1 but not LC3 is accumulated in   

    sarcopenic muscle of mice. J Cachexia Sarcopenia Muscle 7: 204-212, 2016

 

5. Yamaguchi A, Sakuma K, Fujikawa T, Morita I.  Expression of specific IGFBPs is associated with those of the

    proliferating and differentiating markers in regenerating rat plantaris muscle.  J Physiol Sci 63: 71-77, 2013

 

6. Aoi W, Naito Y, Takagi T, Tanimura Y, Takanami Y, Kawai Y, Sakuma K, Hang LP, Mizushima K, Hirai Y, Koyama

    R, Wada S, Higashi A, Kokura S, Ichikawa H, Yoshikawa T.  A novel myokine, secreted protein acidic and rich in

    cysteine (SPARC), suppresses colon tumorigenesis via regular exercise. Gut 62: 882-889, 2013

 

7. Wagatsuma A, Sakuma K.  Myogenic and angiogenic pathways are sequentially activated during postnatal

    muscle regeneration. Current Topics in Peptide and Protein Research 13: 49-59, 2012.

 

8. Sakuma K, Yamaguchi A.  Cyclosporin A inhibits the growth of neonatal MHC-expressing myotubes independent

    of NFATc1 and NFATc3 in the mechanically overloaded soleus muscle of mice. Am J Mol Biol 1: 7-16, 2011

 

9. Hokari F, Kawasaki E, Sakai A, Koshinaka K, Sakuma K, Kawanaka K.  Muscle contractile activity regulates Sirt3

    protein expression in rat skeletal muscles. J Appl Physiol 109: 332-340, 2010

 

10. Akiho MNakashima H, Sakata M, Yamasa Y, Yamaguchi A, Sakuma K.  Expression profile of Notch-1 in

      mechanically overloaded plantaris muscle of mice. Life Sci 86: 59-65, 2010

 

11. Sakuma K, Watanabe K, Hotta N, Koike T, Ishida K, Katayama K, Akima H.  The adaptive responses in several

      mediators linked with hypertrophy and atrophy of skeletal muscle after lower limb unloading in humans.  Acta

      Physiol (Oxf) 197: 151-159, 2009

 

12. Tokugawa S, Sakuma K, Fujiwara H, Hirata M, Oda R, Morisaki S, Yasuhara M, Kubo T.  The expression pattern

      of PKCtheta in satellite cells of normal and regenerating muscle in the rat. Neuropathology 29: 211-218, 2009

 

13. Sakuma KAkiho MNakashima H, Akima H, Yasuhara M.  Age-related reductions in expression of serum

      response factor and myocardin-related transcription factor A in mouse skeletal muscles.  Biochim Biophys Acta

      Mol Basis Dis 1782: 453-461, 2008

 

14. Sakuma KAkiho MNakashima H, Nakao R, Hirata M, Inashima S, Yamaguchi A, Yasuhara M.  Cyclosporin A

      modulates cellular localization of MEF2C protein and blocks fiber hypertrophy in the overloaded soleus muscle

      of mice.  Acta Neuropathol (Berl) 115: 663-674, 2008

 

15. Tanaka Y, Yamaguchi A, Fujikawa T, Sakuma K, Morita I, Ishii K.  Expression of mRNA for specific fibroblast

      growth factors associates with that of the myogenic markers MyoD and PCNA in regenerating and overloaded

      rat plantaris muscle. Acta Physiol (Oxf) 194: 149-159, 2008

 

16. Hirata M, Sakuma K, Okajima S, Fujiwara H, Inashima S, Yasuhara M, Kubo T.  Increased expression of

      neuregulin-1 in differentiating muscle satellite cells and in motoneurons during muscle regeneration. Acta

      Neuropathol (Berl) 113: 451-459, 2007

 

17. Sakuma K, Nakao R, Yamasa Y, Yasuhara M.  Normal distribution of presenilin-1 and nicastrin in skeletal

      muscle and the differential responses of these proteins after denervation.  Biochim Biophys Acta Gen Subj

      1760: 980-987, 2006

 

18. Yamaguchi A, Fujikawa T, Tateoka M, Soya H, Sakuma K, Sugiura T, Morita I, Ikeda Y, Hirai T.  The expression

      of IGF-I and myostatin mRNAs in skeletal muscle of hypophysectomized and underfed rats during postnatal

      growth.  Acta Physiol (Oxf) 186: 291-300, 2006

 

19. Nishikawa J, Sakuma K, Sorimachi Y, Yoshimoto K, Yasuhara M.  Increase of cardiotrophin-1 immunoreactivity

      in regenerating and overloaded but not denervated muscles of rats.  Neuropathology 25: 54-65, 2005

 

20. Sakuma K, Nakao R, Aoi W, Inashima S, Fujikawa T, Hirata M, Sano M, Yasuhara M.  Cyclosporin A treatment

      upregulates Id1 and Smad3 expression and delays skeletal muscle regeneration.  Acta Neuropathol (Berl) 110:

      269-280, 2005

 

21. Fujikawa T, Tamura K, Kawase T, Mori Y, Sakai RR, Sakuma K, Yamaguchi A, Ogata M, Soya H, Nakashima K.

      Prolactin knockdown in the rat paraventricular nucleus by a morpholino-antisence oligonucleotide causes

      hypocalcemia and stress gastric erosion.  Endocrinology 146: 3471-3480, 2005

 

22. Sugiura T, Abe N, Nagano M, Goto K, Sakuma K, Naito H, Yoshioka T, Powers SK.  Changes in PKB/Akt and

      calcineurin signaling during recovery in atrophied soleus muscle induced by unloading.  Am J Physiol Regul

      Integr Comp Physiol 288: 1273-1278, 2005

 

23. Sakuma K, Nakao R, Inashima S, Hirata M, Kubo T, Yasuhara M.  Marked reduction of focal adhesion kinase,

      serum response factor and myocyte enhancer factor 2C, but increase in RhoA and myostatin in the hindlimb dy

      mouse muscles. Acta Neuropathol (Berl) 108: 241-249, 2004

 

24. Aoi W, Naito Y, Takanami Y, Kawai Y, Sakuma K, Yoshida N, Yoshikawa T.  Oxidative stress and delayed-onset

      muscle damage after exercise. Free Radic Biol Med 37: 480-487, 2004

 

25. Yoshida N, Uchiyama K, Kuroda M, Sakuma K, Kokura S, Ichikawa H, Naito Y, Takemura T, Yoshikawa T,

      Okanoue T.  Interleukin-8 expression in the esophageal mucosa of patients with gastroesophageal reflux

      disease.  Scand J Gastroenterol 39: 816-822, 2004

 

26. Sakuma K, Nishikawa J, Nakao R, Watanabe K, Totsuka T, Nakano H, Sano M, Yasuhara M.  Calcineurin is a

      potent regulator for skeletal muscle regeneration by association with NFATc1 and GATA-2. Acta Neuropathol

      (Berl) 105: 271-280, 2003

 

27. Sakuma K, Nishikawa J, Nakao R, Nakano H, Sano M, Yasuhara M.  Serum response factor plays an important

      role in the mechanically overloaded plantaris muscle of rats.  Histochem Cell Biol 119: 149-160, 2003

 

28. Aoi W, Naito Y, Sakuma K, Kuchide M, Tokuda H, Maoka T, Toyokuni S, Oka S, Yasuhara M, Yoshikawa T.

      Astaxanthin limits exercise-induced skeletal and cardiac muscle damage in mice. Antioxid Redox Signal 5:

      139-144, 2003

 

29. Sakuma K, Watanabe K, Totsuka T, Sano M, Nakano H, Nakao R, Nishikawa J, Sorimachi Y, Yoshimoto K,

      Yasuhara M.  The reciprocal change of neurotrophin-4 and glial cell line-derived neurotrophic factor protein in

      the muscles, spinal cord and cerebellum of the dy mouse. Acta Neuropathol (Berl) 104: 482-492, 2002

 

30. Sakuma K, Watanabe K, Sano M, Uramoto I, Nakano H, Li Y-J, Kaneda S, Sorimachi Y, Yoshimoto K, Yasuhara

      M, Totsuka T.  A possible role for BDNF, NT-4 and TrkB in the spinal cord and muscle of rat subjected to

      mechanical overload, bupivacaine injection and axotomy.  Brain Res 907: 1-19, 2001

 

31. Sakuma K, Watanabe K, Sano M, Uramoto I, Totsuka T.  Postnatal profiles of myogenic regulatory factors and

      the receptors of TGF-beta 2, LIF and IGF-I in the gastrocnemius and rectus femoris muscles of dy mouse.

      Acta Neuropathol (Berl) 99: 169-176, 2000

 

32. Sakuma K, Watanabe K, Sano M, Kitajima S, Sakamoto K, Uramoto I, Totsuka T.  The adaptive response of

      transforming growth factor-β2 and -βRII in the overloaded, regenerating and denervated muscles of rats.  Acta

      Neuropathol (Berl) 99: 177-185, 2000

 

33. Sakuma K, Watanabe K, Sano M, Sakamoto K, Uramoto I, Totsuka T.  The adaptive response of MyoD protein

      in the overloaded, regenerating and denervated rat muscles.  Biochim Biophys Acta Gen Subj 1428: 284-292,

      1999

 

34. Sakuma K, Watanabe K, Totsuka T, Uramoto I, Sakamoto K, Sano M.  Differential adaptations of insulin-like

      growth factor, basic fibroblast growth factor and leukemia inhibitory factor in the plantaris muscle of rats by

      mechanical overloading : an immunohistochemical study. Acta Neuropathol (Berl) 95: 123-130, 1998

 

35. Sakuma K, Watanabe K, Totsuka T, Kato K.  Pathological changes in levels of three small stress proteins, αB

      crystallin, HSP 27 and p20, in the hindlimb muscles of dy mouse. Biochim Biophys Acta Mol Basis Dis 1406:

      162-8, 1998

 

36. Totsuka T, Watanabe K, Uramoto I, Sakuma K, Mizutani T.  Muscular dystrophy: centronucleation may reflect a

      compensatory activation of defective myonuclei. J Biomed Sci 5: 54-61, 1998

 

 

37. Sakuma K, Saitoh A, Katsuta S. Denervation-induced region-specific changes in fibre types in the soleus and

      plantaris muscles of rats. Acta Neuropathol (Berl) 93: 129-35, 1997

 

38. Yamaguchi A, Sakuma K, Morita I, Soya H, Takeda H, Katsuta S.  Changes in fibre types in rat soleus and

      plantaris muscles following hypophysectomy and compensatory overload. Acta Physiol Scand 158: 89-95, 1996

 

39. Sakuma K, Yamaguchi A, Katsuta S.  Are region-specific changes in fibre types attributable to nonuniform

      muscle hypertrophy by overloading? Eur J Appl Physiol Occup Physiol 71: 499-504, 1995

 

40. Sakuma K, Yamaguchi A, Ohmori H, Katsuta S.  Nonuniform changes in fibre types in the soleus muscle of the

      developing rat. Eur J Appl Physiol Occup Physiol 70: 132-137, 1995

 

41. Nakano H, Hayashi K, Saitoh A, Sakuma K, Katsuta S.  Oxidative enzyme activity in the rat soleus muscle and

      its motoneurons during postnatal maturation. Brain Res Bull 38: 235-238, 1995

 

42. 佐久間邦弘, 山口明彦, 勝田茂 発育期のラットにおけるヒラメ筋および長指伸筋の酵素活性に及ぼす低栄養の

      影響. 体力科学 42: 155-163, 1993